Publications
Different scales. A shared pursuit of understanding.
My research connects stochastic dynamics, statistical methodology and computational biology. These three threads offer a guide to the work; the complete bibliography below preserves each paper’s original title, authors and publication status.
01 RESEARCH THEME
Stochastic Dynamics & Quantitative Biology
What can fluctuations reveal about living systems?
Connecting molecular observations to stochastic models, with a current focus on fluorescence correlation spectroscopy and photon-counting data.
FCS · Stochastic processes · Semi-Markov models
- Markov renewal & proportional hazards2025 · Preprint
- Brownian motion for biostatistics2024 · Preprint
FCS and photon-counting inference are ongoing research; the linked preprints address stochastic-process methods.
02 RESEARCH THEME
Statistical Methodology
How can we learn more from the measurements we can afford?
Designing informative experiments and developing statistical methods for survival, multistate and biomedical data.
Optimal design · Survival · Multistate models
- Optimal design for nonlinear mixed-effects models2024 · Published article
- Power analysis for preclinical experiments2025 · Published article
- Counting processes & survival analysis2022 · Preprint
Journal articles and methodological preprints, with publication status shown for each record.
03 RESEARCH THEME
Computational Biology & AI
How can computational models make biological variation interpretable?
Modeling single-cell trends and biomedical measurements, alongside work on representation learning and scientific optimization.
scGTM · Single-cell data · Machine learning
- Single-cell generalized trend model2022 · Published article
- Distributional views of glucose monitoring2023 · Published article
- Few-shot class-incremental learning2025 · Published article
Published work spanning biological data analysis and machine learning.
THE COMPLETE RECORD
Publications & Preprints
Browse by publication type, with newest records first within each section. Also on Google Scholar ↗.
Journal & Conference Articles 10
-
DSS-Prompt: Dynamic-Static Synergistic Prompting for Few-Shot Class-Incremental LearningACM Multimedia 2025
-
Impact on Pulp Vitality of Affected Teeth after Decompression for Jaw Cystic LesionsJournal of Endodontics, 51(9), 1170–1176
-
PDXpower: A Power Analysis Tool for Experimental Design in Pre-clinical Xenograft Studies for Uncensored and Censored OutcomesThe New England Journal of Statistics in Data Science, 3(1), 42–54
-
Optimal designs for nonlinear mixed-effects models using competitive swarm optimizer with mutated agentsStatistics and Computing, 34, 156
-
Applications of nature-inspired metaheuristic algorithms for tackling optimization problems across disciplinesScientific Reports, 14, 9403
-
Investigating the value of glucodensity analysis of continuous glucose monitoring data in type 1 diabetes: an exploratory analysisFrontiers in Clinical Diabetes and Healthcare, 4, 1244613
-
Markovian Structures in Modelling SARS-COV-2Journal of Infectious Diseases & Therapy, 10(6), 517
-
Single-cell generalized trend model (scGTM): a flexible and interpretable model of gene expression trend along cell pseudotimeBioinformatics, 38(16), 3927–3934
-
A model-based approach to designing developmental toxicology experiments using sea urchin embryosArchives of Toxicology, 96, 919–932
-
Inference Fusion with Associative Semantics for Unseen Object DetectionProceedings of the AAAI Conference on Artificial Intelligence, 35(3), 1993–2001
Preprints & Working Papers 16
-
Spending Scarce Confirmatory PET Measurements: Target-Aligned Validation in A4/LEARNarXiv:2608.22223 · revised September 2026
-
Domain-Adaptive Cuckoo Search for Structured Statistical Optimization: Applications to Principal Curves, Single-Cell Trajectory Inference, and Exact Experimental DesignSSRN working paper 6669351Related manuscript: Metaheuristics Meets Statistics (2025), with Heather Xihe Yu, Guanghao Qi, and Weng Kee Wong.
-
Crossing the Kolmogorov-Smirnov Boundary: Exact Tails, Sharp Bounds, and Broken PivotsarXiv:2503.11673 · revised May 2026Earlier title: The Kolmogorov-Smirnov Statistic Revisited.
-
Failure of Optimal Design Theory? A Case Study in Toxicology Using Sequential Robust Optimal Design FrameworkarXiv:2503.00002
-
Markov Renewal Proportional Hazards is All You NeedarXiv:2502.03479 · revised September 2025Earlier title: A Tutorial on Markov Renewal and Semi-Markov Proportional Hazards Model.
-
A Semiparametric Bayesian Method for Instrumental Variable Analysis with Partly Interval-Censored Time-to-Event OutcomearXiv:2501.14837
-
Metaheuristics is All You NeedarXiv:2411.05797 · revised March 2025Earlier title: What is Metaheuristics? A Primer for the Epidemiologists.
-
Brownian Motion with a Pulse: A Biostatistician's Guide to Diffusions, Bridges, Functional PCA, and First-Passage ModelsarXiv:2408.16011 · revised June 2026Earlier title: A Tutorial on Brownian Motion for Biostatisticians.
-
A Metric-based Principal Curve Approach for Learning One-dimensional ManifoldarXiv:2405.12390 · revised March 2025
-
A Tutorial on Asymptotic Properties for Biostatisticians with Applications to COVID-19 DataarXiv:2211.07351 · revised September 2024
-
From Risk Sets to Martingales: A Counting-Process Framework for Event-History LearningarXiv:2210.07114 · revised June 2026Earlier title: A Tutorial on Statistical Models Based on Counting Processes.
-
D-optimal Approximate Design for Binary Regression and Quantal Response in Toxicology StudiesarXiv:2209.13191
-
Dual Path Structural Contrastive Embeddings for Learning Novel ObjectsarXiv:2112.12359 · revised January 2022
-
Class-Incremental Few-Shot Object DetectionarXiv:2105.07637 · revised December 2021
-
Particle swarm optimization in constrained maximum likelihood estimation a case studyarXiv:2104.10041
-
Projection Pursuit with Applications to scRNA Sequencing DataarXiv:1912.07602 · revised October 2022
Monograph & Dissertation 2
-
The Statistical CompassTextbook / monograph working manuscript · arXiv:2606.11282Working manuscript, not a publisher-issued book.
-
Nature-inspired Metaheuristics for Biostatistical and Biomedical ResearchPh.D. dissertation, Biostatistics, University of California, Los Angeles
Updated September 2026. Titles and author names follow the linked records. Years indicate publication or first posting; later revisions are noted separately. Published articles and their companion preprints share one entry. Preprints and working manuscripts are not presented as peer-reviewed publications.